Infectious Disease Clinics of North America
Volume 22, Issue 3 , Pages 489-504, September 2008

Tularemia

  • Lise E. Nigrovic, MD, MPH

      Affiliations

    • Division of Emergency Medicine, Children's Hospital, Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    • Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    • Corresponding Author InformationCorresponding author.
  • ,
  • Sarah L. Wingerter, MD

      Affiliations

    • Department of Emergency Medicine, Section of Infectious Diseases, St. Christopher's Hospital for Children, Erie Avenue at Front Street, Philadelphia, PA 19134, USA
    • Drexel University College of Medicine, 2900 W. Queen Lane, Philadelphia, PA 19129, USA

Tularemia is a rare zoonotic infection caused by the bacterium Francisella tularensis. The disease is endemic in North America and parts of Europe and Asia. Arthropods (ticks and deer flies) are the main transmission vector, and small animals (rabbits, hares, and muskrats) serve as reservoir hosts. The clinical presentation depends on the bacterial subspecies and the route of infection. Recent world events have led to a new recognition of F tularensis as a viable agent of bioterrorism, which has sparked a renewed focus on this pathogen.

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PII: S0891-5520(08)00021-4

doi:10.1016/j.idc.2008.03.004

Infectious Disease Clinics of North America
Volume 22, Issue 3 , Pages 489-504, September 2008