Keywords
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Infectious Disease ClinicsReferences
- Ageing and infection.Lancet Infect Dis. 2002; 2: 659-666
- Editorial: the impact of immunosenescence and senescence of immune cells on responses to infection and vaccination.Front Aging. 2022; 3: 882494
- Influence of immune aging on vaccine responses.J Allergy Clin Immunol. 2020; 145: 1309-1321
- Understanding immunosenescence and its impact on vaccination of older adults.Vaccine. 2020; 38: 8264-8272
- The Protective Efficacy of Polyvalent Pneumococcal Polysaccharide Vaccine.N Engl J Med. 1991; 325: 1453-1460
- Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response.J Immunol. 2010; 184: 2518-2527
- Immunosenescence: A systems-level overview of immune cell biology and strategies for improving vaccine responses.Exp Gerontol. 2019; 124: 110632
- The human thymus during aging.Immunol Res. 2000; 22: 253-261
- Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies.J Clin Invest. 2011; 121: 3109-3119
- Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I. Antibody concentrations, avidity and functional activity.Immun Ageing A. 2005; 2: 10
- A study of serum immunoglobulin levels in elderly persons that provides new insights into B cell immunosenescence.Ann N Y Acad Sci. 2006; 1089: 487-495
- B Cell Immunosenescence.Annu Rev Cell Dev Biol. 2020; 36: 551-574
- Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma.Front Immunol. 2017; 8: 706
- Lymphoid tissue fibrosis is associated with impaired vaccine responses.J Clin Invest. 2018; 128: 2763-2773
- Aging of the innate immune system.Curr Opin Immunol. 2010; 22: 507-513
- Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?.Ageing Res Rev. 2021; 71: 101422
- Targeting Inflammation and Immunosenescence to Improve Vaccine Responses in the Elderly.Front Immunol. 2020; 11: 583019
- mTOR inhibition improves immune function in the elderly.Sci Transl Med. 2014; 6: 268ra179
- Influenza.Lancet. 2017; 390: 697-708
- A brief review of influenza virus infection.J Med Virol. 2021; 93: 4638-4646
- CDC. 2009 H1N1 Pandemic. Centers for Disease Control and Prevention.(Available at:) (Accessed July 23, 2022)
- The burden of influenza in older adults: meeting the challenge.Aging Clin Exp Res. 2021; 33: 711-717
- Influenza (Seasonal).(Available at:) (Accessed July 23, 2022)
- CDC. Burden of Influenza. Centers for Disease Control and Prevention.(Available at:) (Published January 7, 2022. Accessed August 20, 2022)
- CDC. Flu & People 65 Years and Older. Centers for Disease Control and Prevention.(Available at:) (Published June 23, 2022. Accessed August 20, 2022)
- Impact of COVID-19 outbreaks and interventions on influenza in China and the United States.Nat Commun. 2021; 12: 3249
- Influenza in the Elderly – A Mini-Review.Gerontology. 2011; 57: 397-404
- Age-Related Differences in Hospitalization Rates, Clinical Presentation, and Outcomes Among Older Adults Hospitalized With Influenza-U.S. Influenza Hospitalization Surveillance Network (FluSurv-NET).Open Forum Infect Dis. 2019; 6: ofz225
- Influenza With and Without Fever: Clinical Predictors and Impact on Outcomes in Patients Requiring Hospitalization.Open Forum Infect Dis. 2020; 7: ofaa268
- Should clinical case definitions of influenza in hospitalized older adults include fever?.Influenza Other Respir Viruses. 2015; 9: 23-29
- The disease burden of influenza beyond respiratory illness.Vaccine. 2021; 39: A6-A14
- Acute myocardial infarctions, strokes and influenza: seasonal and pandemic effects.Epidemiol Infect. 2013; 141: 735-744
- Laboratory-confirmed respiratory infections as triggers for acute myocardial infarction and stroke: a self-controlled case series analysis of national linked datasets from Scotland.Eur Respir J. 2018; 51: AR
- The impact of influenza on functional decline.J Am Geriatr Soc. 2012; 60: 1260-1267
- Secondary Bacterial Infections Associated with Influenza Pandemics.Front Microbiol. 2017; 8: 1041
- Epidemiology and clinical characteristics of hospitalized patients with pandemic influenza A (H1N1) 2009 infections: the effects of bacterial coinfection.Virol J. 2011; 8: 501
- Immunosenescence: influenza vaccination and the elderly.Curr Opin Immunol. 2014; 29: 38-42
- CDC. Types of Influenza Viruses. Centers for Disease Control and Prevention.(Available at:) (Accessed August 16, 2022)
- Influenza Hemagglutinin and Neuraminidase: Yin–Yang Proteins Coevolving to Thwart Immunity.Viruses. 2019; 11: 346
- CDC. Types of Influenza Viruses. Centers for Disease Control and Prevention.(Available at:) (Accessed August 8, 2022)
- Influenza Vaccines: Challenges and Solutions.Cell Host Microbe. 2015; 17: 295-300
- TABLE. Influenza vaccines — United States, 2021–22 influenza season∗ | CDC.(Available at:) (Accessed July 26, 2022)
- Randomized, Double-Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High-Dose and Standard-Dose Influenza Vaccine in Adults 65 Years of Age and Older.J Infect Dis. 2009; 200: 172-180
- Comparative Immunogenicity of Enhanced Seasonal Influenza Vaccines in Older Adults: A Systematic Review and Meta-analysis.J Infect Dis. 2019; 219: 1525-1535
- Efficacy and safety of high-dose influenza vaccine in elderly adults: A systematic review and meta-analysis.Vaccine. 2017; 35: 2775-2780
- Comparative effectiveness of high-dose versus standard-dose influenza vaccination on numbers of US nursing home residents admitted to hospital: a cluster-randomised trial.Lancet Respir Med. 2017; 5: 738-746
- Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults.N Engl J Med. 2014; 371: 635-645
- The mechanism of action of MF59 – An innately attractive adjuvant formulation.Vaccine. 2012; 30: 4341-4348
- Available at:) (Accessed July 19, 2022) (
- Effectiveness of MF59-adjuvanted seasonal influenza vaccine in the elderly: A systematic review and meta-analysis.Vaccine. 2017; 35: 513-520
- Effectiveness of the MF59-adjuvanted trivalent or quadrivalent seasonal influenza vaccine among adults 65 years of age or older, a systematic review and meta-analysis.Influenza Other Respir Viruses. 2021; 15: 813-823
- Cluster-randomized trial of adjuvanted vs. non-adjuvanted trivalent influenza vaccine in 823 U.S. nursing homes.Clin Infect Dis. 2020; https://doi.org/10.1093/cid/ciaa1233
- How Influenza (Flu) Vaccines Are Made | CDC.(Available at:) (Accessed October 25, 2022)
- FluBlok, a recombinant hemagglutinin influenza vaccine.Influenza Other Respir Viruses. 2008; 2: 211-219
- Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older.N Engl J Med. 2017; 376: 2427-2436
- Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains.Proc Natl Acad Sci U S A. 2017; 114: 12578-12583
- Recombinant Influenza (Flu) Vaccine | CDC.(Available at:) (Accessed July 26, 2022)
- Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases.Virulence. 2021; 12: 766-787
Centers for Disease Control and Prevention. 2019. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2019.
- Pneumococcal - Vaccine Preventable Diseases Surveillance Manual | CDC.(Available at:) (Accessed July 29, 2022)
- Bacterial Pneumonia in Older Adults.Infect Dis Clin North Am. 2017; 31: 689-713
- Comprehensive Molecular Testing for Respiratory Pathogens in Community-Acquired Pneumonia.Clin Infect Dis. 2016; 62: 817-823
- Clinical Features of Pneumococcal Disease | CDC.(Available at:) (Accessed August 20, 2022)
- Bacteraemic pneumococcal pneumonia and SARS-CoV-2 pneumonia: differences and similarities.Int J Infect Dis. 2022; 115: 39-47
- Community-Acquired Pneumonia in Very Elderly Patients: Causative Organisms, Clinical Characteristics, and Outcomes.Medicine (Baltimore). 2003; 82: 159-169
- Nonspecific Presentation of Pneumonia in Hospitalized Older People: Age Effect or Dementia?.J Am Geriatr Soc. 2000; 48: 1316-1320
- Streptococcus pneumoniae Capsular Polysaccharide.Microbiol Spectr. 2019; 7: 33
- Streptococcus pneumoniae: virulence factors and variation.Clin Microbiol Infect. 2010; 16: 411-418
- Pneumococcal Vaccination.Microbiol Spectr. 2019; 7: 2
- Pneumococcal Capsules and Their Types: Past, Present, and Future.Clin Microbiol Rev. 2015; 28: 871-899
- Pneumococcal Vaccination Strategies. An Update and Perspective.Ann Am Thorac Soc. 2016; 13: 933-944
- Preventing Pneumococcal Disease in the Elderly.Drugs Aging. 2013; 30: 263-276
- On the mechanisms of conjugate vaccines.Proc Natl Acad Sci U S A. 2019; 116: 14-16
- Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine compared with a 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naive adults.Vaccine. 2013; 31: 3577-3584
- Research C for BE and. PREVNAR 20. FDA.(Available at:) (Accessed August 1, 2022)
Food and Drug Administration. Summary basis for regulatory action— PREVNAR20. Silver Spring, MD: US Department of Health and Human Services, Food and Drug Administration, 2021. https://www.fda.gov/media/150388/download.
- Summary basis for regulatory action—VAXNEUVANCE. Silver Spring, MD: US Department of Health and Human Services.Food and Drug Administration. 2021;
- Pneumococcal Vaccine Recommendations | CDC.(Available at:) (Accessed August 20, 2022)
- The Epidemiology of Herpes Zoster in Immunocompetent, Unvaccinated Adults ≥50 Years Old: Incidence, Complications, Hospitalization, Mortality, and Recurrence.J Infect Dis. 2020; 222: 798-806
- A systematic literature review of herpes zoster incidence worldwide.Hum Vaccin Immunother. 2021; 17: 1714-1732
- Systematic review of incidence and complications of herpes zoster: towards a global perspective.BMJ Open. 2014; 4: e004833
- Influence of Age and Nature of Primary Infection on Varicella-Zoster Virus–Specific Cell-Mediated Immune Responses.J Infect Dis. 2010; 201: 1024-1030
- Herpes Zoster in the Older Adult.Infect Dis Clin North Am. 2017; 31: 811-826
- Immune responses to zoster vaccines.Hum Vaccin Immunother. 2019; 15: 772-777
- A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults.N Engl J Med. 2005; 352: 2271-2284
- Herpes Zoster Vaccine in Older Adults and the Risk of Subsequent Herpes Zoster Disease.JAMA. 2011; 305: 160
- Long-term Persistence of Zoster Vaccine Efficacy.Clin Infect Dis. 2015; 60: 900-909
- Long-Term Effectiveness of the Live Zoster Vaccine in Preventing Shingles: A Cohort Study.Am J Epidemiol. 2018; 187: 161-169
- Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older.N Engl J Med. 2016; 375: 1019-1032
- Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults.N Engl J Med. 2015; 372: 2087-2096
- Recommendations of the Advisory Committee on Immunization Practices for Use of Herpes Zoster Vaccines.MMWR Morb Mortal Wkly Rep. 2018; 67: 103-108
- Use of Recombinant Zoster Vaccine in Immunocompromised Adults Aged ≥19 Years: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022.MMWR Morb Mortal Wkly Rep. 2022; 71: 80-84
- Immunogenicity and Safety of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults Previously Vaccinated with a Live-Attenuated Herpes Zoster Vaccine: A Phase III, Group-Matched, Clinical Trial.Open Forum Infect Dis. 2017; 4: S414
- Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP).MMWR Recomm Rep. 2018; 67: 1-44
- Tetanus surveillance --- United States, 2001-2008.MMWR Morb Mortal Wkly Rep. 2011; 60: 365-369
- Improving vaccination rates in older adults and at-risk groups: focus on pertussis.Aging Clin Exp Res. 2022; 34: 1-8
- The Epidemiology of Nationally Reported Pertussis in the United States, 2000–2016.Clin Infect Dis. 2019; 68: 1634-1640
- Clinical and Epidemiological Aspects of Diphtheria: A Systematic Review and Pooled Analysis.Clin Infect Dis. 2020; 71: 89-97
- Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccines: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2019.MMWR Morb Mortal Wkly Rep. 2020; 69: 77-83
- Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020.MMWR Recomm Rep. 2020; 69: 1-38
- Increase in Hepatitis A Virus Infections — United States, 2013–2018.MMWR Morb Mortal Wkly Rep. 2019; 68: 413-415
- Hepatitis A vaccination and its immunological and epidemiological long-term effects – a review of the evidence.Hum Vaccin Immunother. 2021; 17: 1496-1519
- Hepatitis B.(Available at:) (Accessed July 29, 2022)
- Immunogenicity of a two-dose investigational hepatitis B vaccine, HBsAg-1018, using a toll-like receptor 9 agonist adjuvant compared with a licensed hepatitis B vaccine in adults.Vaccine. 2018; 36: 668-674
- Immunogenicity and safety of a tri-antigenic versus a mono-antigenic hepatitis B vaccine in adults (PROTECT): a randomised, double-blind, phase 3 trial.Lancet Infect Dis. 2021; 21: 1271-1281
- Universal Hepatitis B Vaccination in Adults Aged 19–59 Years: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2022.MMWR Morb Mortal Wkly Rep. 2022; 71: 477-483
- Epidemiology of bacterial meningitis in the USA from 1997 to 2010: a population-based observational study.Lancet Infect Dis. 2014; 14: 813-819
- Current Epidemiology and Trends in Meningococcal Disease—United States, 1996–2015.Clin Infect Dis. 2018; 66: 1276-1281
- Meningococcal Vaccination: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020.MMWR Recomm Rep. 2020; 69: 1-41
- Prevention and control of haemophilus influenzae type b disease: recommendations of the advisory committee on immunization practices (ACIP).MMWR Recomm Rep Morb Mortal Wkly Rep Recomm Rep. 2014; 63: 1-14